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Dosifix® Inline

IV administration set with dosing container. For gravity use.

In gravity infusion, Dosifix® Inline allows a precise dosage of solution which is given to the patient. This functionality is particularly important for neonatal, pediatric and geriatric care. Dosifix® Inline is also used for an intermittent infusion of medication in its correct dilution in a closed system with the ability to flush the IV line after each application for mono and multiple therapy without the need to re-spike.

Advantages

Dosing Function:

Fluid overload in critical illness can have harmful effects and contribute to morbidity and mortality.1,2,3  To prevent the accidental over-infusion of large volumes of fluid, intravenous fluids and transfusions should be given with an in-line burette to ensure that the exact doses of fluids prescribed are administered, especially for neonates and paediatric patients.4 The calibrated 150 ml-dosing container of Dosifix® Inline allows a precise dosage of solution which is given to the patient and thus reduces the risk of overdosage.5

Admixture Function:

Due to its admixture port on top of the dosage container, Dosifix® Inline can be used for an intermittent infusion of medication in its correct dilution with the ability to flush the IV line after each application.5

Flushing Function:

Being connected to an IV container with neutral solution (e.g. NaCl 0.9 %)  Dosifix® Inline provides the possibility to flush the entire IV line after each drug.5 Flushing helps to prevent the risk of drug incompatibilities when giving multiple doses of intermittent infusions of different drugs and reduces the residual volume of highly effective medication which decreases the risk of therapy failure caused by substance loss.6, 7

Functional Hanger Design for stabilization of the Dosifix® Inline dosing container.5

Highlighted scaling values for visualization of fluid level. 5

Closed System:

Being connected to an IV container with neutral solution (e.g. NaCl 0.9 %) and equipped with the needle-free, self-sealing Safeflow port on top of the burette as well as a swimmer with membrane, Dosifix® Inline forms a Closed System acc. to NIOSH. It prevents microbial ingress and the escape of any solution or contaminants into the adjacent environment.6, 8

Technical data:

  • Available with needle-free Safeflow of Safsite port
  • Pressure resistant up to 0.5 bar.5
  • Can be used with luer compatible devices in compliance with DIN EN 1707.5
  • Can be used with closures for infusion bottles acc. to DIN EN ISO 8536-2.5
  • Can be used with IV administration sets in conformity with DIN EN 8536-4.5
  • Total set length Inline Sets: 50 cm (10 cm below burette).5
  • Not made with DEHP.5
  • Not made with latex.5
  • Dosifix® Inline should be changed acc. to national guidelines (e.g. CDC) and / or institutional protocols.5
  • Dosifix® Inline can be used for all patients (adults, pediatric and neonates) for which infusion therapy is prescribed. No gender- or age-related limitations.5
  • Mind the instructions for use of the complementary used IV administration set.

1  Ker, G. L., Gangadharan, S. (2018): Management of Fluid Overload in the Pediatric ICU, Pediatric Critical Care, July 2018, pp. 193–209.

2  Foland, J.A., Fortenberry, J.D., Warshaw, B. L. et al. (2004): Fluid overload before continuous hemofiltration and survival in critically ill children: a retrospective analysis, Crit Care Med. 2004 Vol. 32, No. 8, pp. 1771–1776.

Del Granado, R. C. and Mehta, R. L. (2016): Fluid overload in the ICU: evaluation and management, Nephrology 17, p. 109.

4  WHO (2013): Hospital Care for Children. Guidelines for the Management of Common Childhood Illnesses, 2nd edition. Geneva.

5  Engineering data on file.

6  Plagge, H., Golmich, J., Brnanad, D., et al. (2010): Evaluation of the dead volume in intravenous short-term infusion, Pharma Publishing and Media Europe, Volume 16, Issue 2, pp. 31-37.

7  Federal Institute of Drugs and Medicinal Devices (2015): The Forgotten Residue: Dead Volumes of Short-term Infusions, Pub. No. 2, June 2015.

8  National Institute for Occupational Safety and Health (2004): NIOSH alert 2004-165. Preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings, CDC, Cincinnati, OH.

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